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   Table 2. Effects of Muraru peel ethanol extract on blood parameters in the acute toxicity study.

Parameters

Units

500mg/kg

1000mg/kg

2000mg/kg

Control

p-value

RBC

106 /μL

7.32± 0.19

7.23± 0.12

7.72± 0.17

7.93± 0.04

0.1387

HB

g/dL

13.15±0.32

13.40± 0.17

14.10± 0.25

13.68± 0.09

0.0570

HCT

%

37.35± 0.55

39.85± 2.26

38.03± 1.11

38.80± 0.52

0.5887

MCV

fL

55.85± 0.79

54.15± 0.39

54.45± 1.14

54.28± 1.16

0.5541

MCH

Pg

20.20± 0.76

19.15± 0.24

19.85± 0.52

18.68± 0.06

0.1587

MCHC

g/dL

34.83± 0.46

35.45± 0.35

37.33± 1.12

34.68± 0.45

0.0565

PLT

103/μL

781± 4.42

796.50± 9.08

804.75± 9.66

808.25± 4.35

0.0889

MPV

fL

6.90± 0.27

7± 0.25

6.73± 0.11

6.75± 0.12

0.7471

WBC

103/μL

6.28± 0.11

6.31± 0.12

6.22± 0.11

6.55± 0.06

0.8813

NEU

103/μL

0.715± 0.02

0.75± 0.08

0.88± 0.06

0.89± 0.03

0.0595

LYM

103/μL

3.72± 0.20

3.87± 0.11

3.55± 0.18

4.06± 0.07

0.1541

MON

103/μL

0.01± 0.00

0.03± 0.01

0.02± 0.0

0.02± 0.0

0.3162

EOS

103/μL

0.02± 0.01

0.01± 0

0.01± 0.00

0.02± 0.01

0.2030

NEU %

%

11.42± 0.42

11.88± 1.03

14.26± 0.86

13.64± 0.48

0.0542

LYM %

%

59.31± 3.61

61.43± 1.85

57.09± 3.43

62± 0.68

0.5721

MON %

%

0.2± 0.04

0.40± 0.1

0.36± 0.04

0.34+-0.10

0.3274

AST

μ/L

113.50± 14.34

117.25± 17.38

119.38± 18.94

114.95± 13.84

0.9943

ALT

μ/L

56.65± 5.68

55.40± 5.19

62.83± 2.32

64.48± 2.91

0.3871

Creatinine

mg/dL

0.49± 0.03

0.50± 0.04

0.54± 0.03

0.50± 0.04

0.8314

Urea

mg/dL

50.65± 3.25

50.68± 0.77

58.15± 9.44

47.20± 3.44

 

 RBC: Total red blood cell count; HB: hemoglobin; HCT: Hematocrit; MCV: Mean corpuscular volume; MCH: Mean corpuscular hemoglobin; MCHC:   Mean corpuscular hemoglobin concentration; PLT: Platelet count; MPV: Mean platelet volume; WBC: Total white blood cell count; NEU: Neutrophils; LYM: Lymphocytes; MON: Monocytes; EOS: Eosin; %: Percentage. All values are expressed as a mean ± SEM (n = 3).