Table 3. Effects of Muraru peel hydroethanolic extract on blood parameters in the subacute toxicity.
|
Parameters |
Units |
250mg/kg |
500mg/kg |
Control |
p-value |
|
RBC |
106 /μL |
7.81± 0.09 |
7.82± 0.05 |
8.55± 0.21 |
0.0693 |
|
HB |
g/dL |
14.50± 0.55 |
15.13± 0.06 |
15.73± 0.17 |
0.0526 |
|
HCT |
% |
41.85± 1.81 |
41.85± 1.81 |
42.20± 1.64 |
0.6956 |
|
MCV |
fL |
55.85± 1.30 |
55.40± 1.09 |
55.25± 1.74 |
0.9376 |
|
MCH |
Pg |
19.40± 0.45 |
19.23± 0.31 |
19.33± 0.67 |
0.7968 |
|
MCHC |
g/dL |
34.75± 0.22 |
34.75± 0.36 |
34.93± 0.30 |
0.1109 |
|
PLT |
103/μL |
877.75± 10.25 |
864.75± 9.41 |
897.50± 1.50 |
0.1100 |
|
MPV |
fL |
7.48± 0.58 |
7.28± 0.32 |
6.25± 0.34 |
0.1966 |
|
WBC |
103/μL |
5.87± 0.37 |
6.43± 0.59 |
5.98± 0.32 |
0.8382 |
|
NEU |
103/μL |
0.84± 0.19 |
1.43± 0.07 |
1.30± 0.11 |
0.0869 |
|
LYM |
103/μL |
4.05± 1.21 |
4.70± 0.33 |
4.51± 0.19 |
0.7641 |
|
MON |
103/μL |
0.01± 0.00 |
0.02± 0.0 |
0.02± 0.0 |
0.3186 |
|
EOS |
103/μL |
0.01± 0.0 |
0.2+-0.2 |
0± 0.0 |
0.4465 |
|
NEU % |
% |
14.37± 3.27 |
22.92± 2.78 |
21.69± 0.9 |
0.1027 |
|
LYM % |
% |
68± 19.60 |
74.14+-5.14 |
75.66+-2.81 |
0.7504 |
|
MON % |
% |
0.40± 0.10 |
0.36± 0.08 |
0.34+-0.08 |
0.9593 |
|
AST |
μ/L |
111.33± 9.60 |
136.40± 12.28 |
114.38± 9.43 |
0.2762 |
|
ALT |
μ/L |
48.63± 1.26 |
52.52± 2.77 |
46.65± 9.47 |
0.8190 |
|
Creatinine |
mg/dL |
0.50± 0.02 |
0.48± 0.03 |
0.44± 0.03 |
0.0940 |
|
Urea |
mg/dL |
50.40± 1.04 |
48.63± 1.64 |
48.10± 1.51 |
0.3320 |
RBC: Total red blood cell count; HB: hemoglobin; HCT: Hematocrit; MCV: Mean corpuscular volume; MCH: Mean corpuscular hemoglobin; MCHC: Mean corpuscular hemoglobin concentration; PLT: Platelet count; MPV: Mean platelet volume; WBC: Total white blood cell count; NEU: Neutrophils; LYM: Lymphocytes; MON: Monocytes; EOS: Eosin; BAS: Basophiles; %: Percentage. Values are expressed as a mean ± SEM (n = 3 rats/group and p < 0.05).